American Hospital Dubai, Mohamed & Obaid Al Mulla Group, has entered into a joint venture with Livio AB to build an Ultra-Fertility laboratory that follows the highest international standards. The lab will provide patients with comprehensive fertility care and accessible treatments.
The team of highly experienced fertility doctors at Conceive Fertility IVF Clinic Sharjah is committed to providing world class treatment right here in UAE. They use innovative technology and advanced procedures to achieve excellent pregnancy rates.
In Vitro Fertilization (IVF)
IVF is a fertility treatment that involves the fertilization of an egg and sperm outside the body. The embryos are then implanted in the woman’s uterus. The procedure is recommended if other infertility treatments such as fertility medications and intrauterine insemination have failed to result in pregnancy.
IVF is contraindicated in women who have significant medical conditions that may cause severe morbidity and mortality if the pregnancy was to succeed (NYHA class 3 or 4 heart failure, Eisenmenger syndrome, aortic stenosis, coarctation of aorta etc.). However, in such cases, the women can opt for oocyte aspiration and sperm donation from the partner or a gestational carrier.
The UAE has recently made strides in fertility preservation by allowing individuals to freeze their eggs or sperm for a period of 5 years (extendable upon request). This will significantly reduce the costs of future IVF cycles and increase the chances of pregnancy. Moreover, the new law will also benefit individuals who are undergoing medical treatments that affect their fertility and those who choose to get married at an older age.
In Vitro Sperm Implantation (IVSI)
If you have unexplained infertility or low sperm count, ICSI can improve your chances of conception. This process involves injecting a single sperm directly into an egg. The fertilized egg is then transferred into your uterus.
With traditional IVF, your healthcare provider places thousands of sperm next to an egg in a laboratory dish. Then they wait to see if one sperm fertilizes the egg. If the fertilization doesn’t happen, conception doesn’t occur.
With ICSI, your doctor injects a single sperm directly into an individual egg. Then they watch for signs of fertilization, which typically occurs within five to six days. After fertilization, the healthy fertilized egg is called an embryo. They may transfer it to your uterus after 2 or 3 days, or they may cryopreserve the remaining good-quality embryos for future use. In clinical studies, ICSI has shown similar pregnancy rates compared to conventional in vitro fertilization with fresh eggs in couples who don’t have male factor infertility.
Preimplantation Genetic Diagnosis (PGD)
In PGD, an embryo is screened for specific inherited diseases and other structural changes in the chromosomes. It is commonly used for monogenic (single-gene) diseases and chromosomal abnormalities such as Down syndrome.
Embryos are biopsied on days three or five of the IVF cycle, before transfer into the uterus. This allows the embryos to be identified for health and sex selection. Embryos found to be healthy are then transferred into the woman’s uterus while those that have a chromosomal abnormality or disease are frozen for future use.
Gender selection through PGD was first popularized in the novel My Sister’s Keeper, where the main character was created through PGD to be a genetic match for her APL positive sister so she could donate bone marrow to her at birth. This is now an option for many couples. Clinic 1’s website also articulates the safety of PGD and sex selection noting that “embryos without chromosomal abnormalities have an increased pregnancy rate and reduced miscarriage rates.”
Preimplantation Genetic Screening (PGS)
PGS, or PGT-A as it is commonly referred to, is used to improve implantation rates in IVF treatment. It does so by identifying embryos with an abnormal number of chromosomes, which can lead to miscarriage or other problems if carried to term.
Embryos are usually biopsied at the cleavage or blastocyst stage. A small sample is then microsurgically removed without significantly affecting the health of the embryo, and a genetic test is performed using various techniques. The results are then reviewed and an informed decision is made about which embryos should be transferred into the uterus.
Unlike PGD, which examines each individual gene for a specific genetic mutation, PGS looks at all of the chromosomes in an embryo and can identify aneuploidy using a number of methods including PCR, FISH and now array comparative genomic hybridization and next generation sequencing (NGS). It is important to note that PGS cannot be used to select for particular traits or to create “designer babies.” PGS only helps increase pregnancy rates by discarding abnormal embryos and selecting those most likely to result in a healthy live birth.